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An antispasmodic drug, which removes pain and reduces the tone of smooth muscles: gastrointestinal tract, biliary tract, uterus, it also relaxes the detrusor direct antispasmodic and m-anticholinergic effect. Well tolerated when appointed for a long term. Used in neurogenic bladder including detrusor hyperreflexia, multiple sclerosis or spina bifida, urinary incontinence of idiopathic origin, nocturnal enuresis in children older than 5 years. This is exactly how your parcel will look like pictures of a real shipping item. It has a size and a look of a regular private letter 9.

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Antimuscarinic medications are used to treat nonneurogenic overactive bladder refractory to nonpharmacologic therapy. Side effects such as dry mouth, constipation, blurred vision, dizziness, and impaired cognition limit the tolerability of therapy and are largely responsible for high discontinuation rates. Oxybutynin is a potent muscarinic receptor antagonist whose primary metabolite after first-pass hepatic metabolism is considered largely responsible for its associated anticholinergic side effects. Transdermal administration of medications bypasses hepatic processing. Transdermal oxybutynin is available as a patch that is changed every 3—4 days, a gel available in individual sachets, or via a metered-dose pump that is applied daily. Idiopathic, nonneurogenic overactive bladder OAB represents a significant public health burden, affecting 1 out of 7 US women Hartmann et al.

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