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Bupropion is a special antidepressant in the NDRI family. Bupropion is approved by the FDA for the treatment of major depressive disorder MDD, seasonal affective disorder, and smoking cessation in combination with nicotine replacement therapy. This can ease symptoms of depression.

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It has been wellbutrin bought online uk under the trade name Zyban. It also has several off-label uses and has since been approved to treat other conditions. It has proven an effective antidepressant for many depressive conditions, including bipolar disorder. Treating mental health illnesses is most effective with behavioural therapies and counselling.