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There were total exposures. Forty percent of the cohort was female. From to, exposures increased from to with a rise in incidence from 4. Acute on chronic exposures increased from Initially prescribed for adults with hypertension, it has since been applied to other clinical contexts including opioid withdrawal, anxiety, and other psychiatric disorders. Emergency providers thus need to be aware of this drug as a potential cause for altered mental status or hemodynamic changes in the pediatric patient.
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