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COVID is an emerging, rapidly evolving situation. Warning You have reached the maximum number of saved studies Listing a study does not mean it has been evaluated by the U. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. The purpose of this study is to evaluate the non-inferiority clinical efficacy of two different drug associations in the essential hypertension control. Primary Outcome Measures: Efficacy of essential hypertension control based on the reduction of systolic blood pressure at the end of the study. Inclusion Criteria: Signed Consent of the patient; Participants with decompensated essential hypertension, classified into stage 1 with high or very high cardiovascular risk, stage 2 or stage 3 according to the Brazilian Society of Cardiology, who are being treated with monotherapy.

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Purpose: As hypertension HT is one of the risk factors for lower urinary tract symptoms, we investigated the effect of an angiotensin II type I receptor blocker, olmesartan, on bladder dysfunction in the spontaneously hypertensive rat SHR. Wistar rats were used as normotensive controls. Treatment with olmesartan and nifedipine significantly improved BP. However, only olmesartan significantly ameliorated urodynamic parameters and oxidative damage compared to the non-treated SHR. Olmesartan significantly ameliorated this bladder dysfunction. Keywords: bladder blood flow; bladder dysfunction; olmesartan; spontaneously hypertensive rat.

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