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Receive personal and immediate responses to your questions from IsraelPharm's pharmacist. Lamotrigine Lamictal is used alone or with other medications to prevent or control seizures epilepsy in people aged 2 and older. It may also be used to help prevent the extreme mood swings of bipolar disorder in people aged 18 and older. This medication is an anticonvulsant. Lamotrigine is thought to work by restoring the balance of certain natural neurotransmitters in the brain. Lamotrigine is used in epilepsy.

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Lamotrigine 3,5-diamino 2,3-dicholorophenyl -1,2,4-triazine is a phenyyltriazine with a molecular weight of From: Handbook of Clinical Neurology, Lamotrigine, a phenyltriazine anticonvulsant, is a newer antiepileptic drug, introduced for treatment of seizure disorders in the early 90s. It exerts its antiseizure activity by blocking voltage-activated sodium channels, thereby preventing the presynaptic release of the excitatory neurotransmitters. The pharmacokinetics of Lamotrigine was studied after single and multiple doses in healthy volunteers and epileptic patients. The risk of adverse effects including hypersensitivity reactions and tremor is increased when lamotrigine is combined with valproic acid.

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