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- The aim of this study was to evaluate the long-term efficacy and tolerability of etoricoxib, a COX-2 selective inhibitor, in osteoarthritis OA patients.
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Objective: To assess the efficacy, safety, and tolerability of etoricoxib, a cyclooxygenase 2 COX-2 selective inhibitor, administered continuously over 52 weeks for the treatment of ankylosing spondylitis AS. The primary outcome measures on mm visual analog scales were patient's assessment of spine pain, patient's global assessment of disease activity, and the Bath Ankylosing Spondylitis Functional Index. Results: Of the patients randomized to receive treatment,
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The list of product names concerned is given in Annex I. This referral has been replaced by Article 13 referrals. Etoricoxib is a selective inhibitor of COX-2 cyclooxygenase 2 indicated in the symptomatic relief of osteoarthritis OA, mg once daily od, rheumatoid arthritis RA, 90mg od and the pain and signs of inflammation associated with acute gouty arthritis mg od This referral procedure relates to a request for arbitration concerning a type II variation for a new indication to include treatment of ankylosing spondylitis AS, at a recommended daily dose of 90mg.

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