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Indications And Clinical Uses: Endocrine Disorders: Primary or secondary adrenocortical insufficiency hydrocortisone or cortisone are the drugs of choice although synthetic analogs may be used in conjunction with mineralocorticoids where applicable; mineralocorticoid supplementation is of particular importance when treating this condition in infants ; nonsuppurative thyroiditis; hypercalcemia associated with cancer. Rheumatic Disorders: As adjunctive therapy for short-term administration to tide the patient over an acute episode or exacerbation in psoriatic arthritis; rheumatoid arthritis selected cases may require low dose maintenance therapy ; ankylosing spondylitis; acute and subacute bursitis; acute nonspecific tenosynovitis; and acute gouty arthritis, synovitis of osteoarthritis, epicondylitis. Collagen Diseases: for use during an exacerbation or as maintenance therapy in selected cases of systemic lupus erythematosus and acute rheumatic carditis. Severe seborrheic dermatitis. Ophthalmic Diseases: severe acute and chronic allergic and inflammatory processes involving the eye and its associated anatomic parts such as allergic conjunctivitis, keratitis, allergic corneal marginal ulcers, herpes zoster ophthalmicus, iritis and iridocyclitis, chorioretinitis, anterior segment inflammation, diffuse posterior uveitis and choroiditis, optic neuritis, and sympathetic ophthalmia. Hematologic Disorders: idiopathic and secondary thrombocytopenia in adults, acquired autoimmune hemolytic anemia, erythroblastopenia RBC anemia, and congenital erythroid hypoplastic anemia. Neoplastic Diseases: palliative management of leukemias and lymphomas in adults and acute leukemia of childhood.

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