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While celecoxib may be appropriate for a small number of patients, our reservations about it remain strong. Here's why: It's probably harder on the heart. Although the evidence is mixed, some meta-analyses, which assess the combined data from many clinical trials, have linked celecoxib at higher or more frequent doses to an increased likelihood of heart attack compared with either a placebo or naproxen. And the AHA says celecoxib should be used to treat people at risk of heart attack only if other measures have failed. That recommendation is based mainly on the ways that celecoxib acts in the body, which in theory may harm the heart more than other NSAIDs.

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This leaflet answers some common questions about Celebrex. All medicines have risks and benefits. Your doctor has weighed the risks of you taking Celebrex against the benefits it is expected to have for you. If you have any concerns about taking this medicine, ask your doctor or pharmacist. Although Celebrex can relieve the symptoms of pain and inflammation, it will not cure your condition.

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