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This non-approvable letter was due to safety concerns of an increased risk of cardiovascular events including heart attack and stroke and questions on the benefit-risk ratio in patients taking Arcoxia. Merck will continue to market Arcoxia outside the United States. Your doctor will want discuss your treatment with Arcoxia from time to time. It is important that you use the price of arcoxia dose that controls your pain and you should not take Arcoxia for longer than necessary.

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