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Quetiapine is available as the brand-name drugs Seroquel immediate-release tablet and Seroquel XR extended-release tablet. Quetiapine may be used as part of a combination therapy. This means you may need to take it with other medications. Quetiapine oral tablet is used to treat the symptoms of schizophrenia, bipolar disorder, or depression. Quetiapine can be used to treat symptoms in adults who have depressive episodes or manic episodes caused by bipolar I disorder. For these cases, it can be used alone or with the drugs lithium or divalproex. It can also be used with lithium or divalproex for long-term treatment of bipolar I disorder.

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Divalproex sodium, valproate sodium, and valproic acid, are all similar medications that are used by the body as valproic acid. Therefore, the term valproic acid will be used to represent all of these medications in this discussion. Valproic acid may cause serious or life-threatening damage to the liver that is most likely to occur within the first 6 months of therapy. The risk of developing liver damage is greater in children who are younger than 2 years of age and are also taking more than one medication to prevent seizures, have certain inherited diseases that may prevent the body from changing food to energy normally, or any condition that affects the ability to think, learn, and understand. Tell your doctor if you have a certain inherited condition that affects the brain, muscles, nerves, and liver Alpers Huttenlocher Syndrome, urea cycle disorder an inherited condition that affects the ability to metabolize protein, or liver disease.

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General Population: Hepatic failure resulting in fatalities has occurred in patients receiving valproate and its derivatives. These incidents usually have occurred during the first six months of treatment. Serious or fatal hepatotoxicity may be preceded by non-specific symptoms such as malaise, weakness, lethargy, facial edema, anorexia, and vomiting. In patients with epilepsy, a loss of seizure control may also occur. Patients should be monitored closely for appearance of these symptoms. Children under the age of two years are at a considerably increased risk of developing fatal hepatotoxicity, especially those on multiple anticonvulsants, those with congenital metabolic disorders, those with severe seizure disorders accompanied by mental retardation, and those with organic brain disease.

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Sodium valproate is used to treat epilepsy and bipolar disorder. It's occasionally used to prevent migraine headaches. It also comes as granules that you mix with food or drink. Depakote 800mg otc valproate can also be given by injection, but this is usually only done in hospital. If taken during pregnancy, sodium valproate can cause problems for a baby's development, including birth defects and long term learning difficulties.