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It's thought to work by increasing the amount or mimicking the action of a neurotransmitter, GABA, in the brain, but the exact mechanism is unknown. Increasing levels of GABA may help prevent brain signals that lead to seizures. It was approved to treat bipolar disorder in, and in it was approved for use as a migraine prevention medication. Abbot Laboratories manufactures Depakote. In, Abbot Laboratories pleaded guilty to federal charges for marketing Depakote as a drug to control agitation and aggression in elderly nursing home patients. The FDA requires Depakote to carry a black-box warning because it can cause serious liver damage that could be fatal, especially in children younger than 2.
Clonazepam may increase the risk of serious or life-threatening breathing problems, sedation, or coma if used along with certain medications. Your doctor may need to change the dosages of your medications and will monitor you carefully. Do not take a larger dose, take it more often, or for a longer time than your doctor tells you to. Do not drink alcohol or use street drugs during your treatment. Drinking alcohol or using street drugs during your treatment with clonazepam also increases the risk that you will experience these serious, life-threatening side effects.
