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Author: Eli Lilly Nederland B. ZYPREXA is used to treat a disease with symptoms such as hearing, seeing or sensing things which are not there, mistaken beliefs, unusual suspiciousness, and becoming withdrawn. People with this disease may also feel depressed, anxious or tense. ZYPREXA is used to treat a condition with symptoms such as feeling high, having excessive amounts of energy, needing much less sleep than usual, talking very quickly with racing ideas and sometimes severe irritability. It is also a mood stabiliser that prevents further occurrences of the disabling high and low depressed extremes of mood associated with this condition. An allergic reaction may be recognised as a rash, itching, a swollen face, swollen lips or shortness of breath.

Find out why Zyprexa Olanzapine is prescribed, side effects of Zyprexa, Zyprexa warnings, effects of Zyprexa during pregnancy, more - in plain English. Zyprexa helps manage symptoms of schizophrenia, the manic and mixed phases of bipolar disorder, and other psychotic disorders. Zyprexa may also be used with lithium or valproate for short-term treatment of acute manic episodes of bipolar disorder. Zyprexa is thought to work by opposing the action of serotonin and dopamine, two of the brain's major chemical messengers. The drug is available as Zyprexa tablets and Zyprexa Zydis, which dissolves rapidly with or without liquid.

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Consequently, palliative care clinicians may utilize it to target multiple symptoms common among their patients. In addition to antagonizing dopamine receptors in the CNS nausea, delirium, it blocks serotonin 5HT2 receptors insomnia, anxiety, cachexia and is anticholinergic Adverse Reactions and Cautions When compared to other antipsychotics, olanzapine causes fewer extrapyramidal symptoms 5 and has lesser effect on the QTc interval compared to IV haloperidol 6, but it may have a higher prevalence of somnolence 7 and weight gain 8,9. Weight gain is even more apparent in children than adults No dosage adjustments are required for patients with renal or hepatic impairment, although caution is recommended in end stage liver disease.

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What is olanzapine, and how does it work mechanism of action? Olanzapine is a drug that is used to treat schizophrenia and acute manic episodes associated with bipolar I disorder. Olanzapine belongs to a drug class known as atypical antipsychotics. Other members of this class include zyprexa 3 mg Clozaril, risperidone Risperdal, aripiprazole Abilify and ziprasidone Geodon. The exact mechanism of action of olanzapine is not known.

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Olanzapine at a 5-mg dose, when combined with aprepitant, palonosetron, and dexamethasone, significantly reduced the risk of delayed nausea and vomiting in patients receiving cisplatin-based chemotherapy, according to new research. The study investigators believe this approach may be considered a new standard antiemetic therapy. A randomized, double-blind, placebo-controlled phase III trial evaluated olanzapine at 5 mg combined with standard antiemetic therapy in patients receiving cisplatin-based chemotherapy. This study did not directly compare olanzapine at 5 mg to olanzapine at a mg dose; however, the study results demonstrated equivalent activity and favorable toxicity when compared to the initial study employing the buy generic avodart standard dose. Wulff-Burchfield, these findings are practice-changing. There is no excuse for anyone to be vomiting after chemotherapy in the modern era.

zyprexa 3 mg


Olanzapine is a dopamine D 1, D 2, D 4, 5-HT 2, histamine- 1- and muscarinic-receptor antagonist. Acute myocardial infarction; bradycardia; recent heart surgery; severe hypotension; sick sinus syndrome; unstable angina. An ECG may be required, particularly if physical examination identifies cardiovascular risk factors, personal history of cardiovascular disease, or if the patient is being admitted as an inpatient. See also Prescribing buy generic avodart the elderly. Bone-marrow depression; hypereosinophilic disorders; low leucocyte count; low neutrophil count; myeloproliferative disease; paralytic ileus. Agranulocytosis; confusion; embolism and thrombosis; neuroleptic malignant syndrome discontinue—potentially fatal.

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Olanzapine belongs to group of medications known as antipsychotic agents. Schizophrenia can cause symptoms such as hallucinations e. People with zyprexa 3 mg condition may also feel depressed, anxious, or tense. Bipolar disorder can cause alternating periods of depression and mania abnormally elevated or irritable mood or mixed episodes where people have symptoms of both depression and mania. Olanzapine may be used, alone or in combination with other medications, to treat the manic or mixed episodes but not the depression of bipolar disorder.

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Analyses of seventeen placebo-controlled trials modal duration of 10 weeks, largely in patients taking atypical antipsychotic drugs, revealed a risk of death in drug-treated patients of between 1. The chemical designation is 2-methyl 4-methylpiperazinyl H -thieno benzodiazepine.



  • Solid and dotted lines indicate regression trend lines.
  • Her COPD improved but she developed delirium.
  • When you receive olanzapine extended-release injection, the medication is usually released slowly into your blood over a period of time.
  • All FDA black box warnings are at the end of this fact sheet.
  • Olanzapine sold under the trade name Zyprexa among others is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder.

Debilitated, risk of hypotension, or sensitive to olanzapine: 2. Severe orthostatic hypotension: additional dose not recommended.

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Olanzapine is an antipsychotic medication that is used to treat psychotic conditions such as schizophrenia and bipolar disorder manic depression in adults and children at least 13 years old. Olanzapine is also used together with fluoxetine Prozac to treat episodes of depression in adults and children at least 10 years old who have bipolar I disorder.

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A governmentally-recognized ID which uniquely identifies the product within its regulatory market. Olanzapine was initially used orally and intramuscularly for the chronic treatment of schizophrenia in patients over 13 years old and other psychiatric disorders such as bipolar I disorder including mixed or manic episodes. Olanzapine is also indicated, in combination with lithium or valproate for the short-term treatment of acute manic or mixed episodes associated with bipolar I disorder in adults. As well, olanzapine is indicated, in combination with fluoxetine for the treatment of episodes of depression associated with bipolar disorder type 1 and treatment-resistant depression in patients over 10 years old. Olanzapine is also approved for the management of psychomotor agitation associated with schizophrenia and bipolar I mania. Schizophrenia is a complex biochemical brain disorder that affects the person's ability to differentiate reality.


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