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The effects of naproxen on renal function in 34 patients with minimally elevated serum creatinine Scr or subnormal creatinine clearance Ccr order naprosyn 375 evaluated in a parallel-design study. Renal function was assessed by Scr, Ccr, and BUN measurements at baseline and at the end of each treatment phase. During the first 2 weeks of treatment with naproxen mg twice daily, there was no change in Scr.

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