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Discontinuing an antidepressant medication usually involves reducing your dose in increments, allowing two to six weeks or longer between dose reductions. Your clinician can instruct you in tapering your dose and prescribe the appropriate dosage pills. In some cases, you can use a pill cutter to create smaller-dose pills, though be sure to check with your clinician or pharmacist to find out if your antidepressant can be cut. Your tapering schedule will depend on which antidepressant you're taking, how long you've been taking it, your current dose, and any symptoms you had during previous medication changes. However, depending on how you respond to each dose reduction, you may want to taper more gradually using smaller dose reductions, longer intervals between dose reductions, or both. If you experience discontinuation symptoms after a particular dose reduction, you may want to add back half the dose — or all of it — and continue from there with smaller dose reductions.

If you have depression, anxiety, or pain, your doctor may prescribe duloxetine oral capsules for you. Duloxetine is classified as a selective norepinephrine reuptake inhibitor SNRI. The capsules are delayed-release, which means the drug gets released into your body a certain amount of time after you take the capsule. Note: Duloxetine also comes as sprinkle capsules that you can open and pour onto food. Duloxetine oral capsule is a generic drug. In general, generics usually cost less than brand-name drugs.

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Bleeding disorders; cardiac disease; elderly; history of mania; history of seizures; hypertension avoid if uncontrolled ; raised intra-ocular pressure; susceptibility to angle-closure glaucoma. Anxiety; appetite decreased; constipation; diarrhoea; dizziness; drowsiness; dry mouth; fall; fatigue; flushing; gastrointestinal discomfort; gastrointestinal disorders; headache; muscle complaints; nausea; pain; palpitations; paraesthesia; sexual dysfunction; skin reactions; sleep disorders; sweat changes; tinnitus; tremor; urinary disorders; vision disorders; vomiting; weight changes; yawning. Apathy; arrhythmias; behaviour abnormal; burping; chills; concentration impaired; disorientation; dysphagia; ear pain; feeling abnormal; gait abnormal; haemorrhage; hepatic disorders; hyperglycaemia; increased risk of infection; malaise; menstrual disorder; movement disorders; mydriasis; peripheral coldness; photosensitivity reaction; postural hypotension; suicidal behaviours; syncope; taste altered; temperature sensation altered; testicular pain; thirst; throat tightness; vertigo. Angioedema; cutaneous vasculitis; dehydration; galactorrhoea; glaucoma; hallucination; hyperprolactinaemia; hypertensive crisis; hyponatraemia; hypothyroidism; mania; menopausal symptoms; oral disorders; seizure; serotonin syndrome; SIADH; Stevens-Johnson syndrome; urine odour abnormal. Toxicity in animal studies—avoid in patients with stress urinary incontinence; in other conditions use only if potential benefit outweighs risk. Risk of neonatal withdrawal symptoms if used near term.

In addition to depression, doctors can prescribe Cymbalta to treat anxiety that lasts for at least six months, pain from diabetic nerve damage, fibromyalgia, and long-term muscle or bone pain. It works by increasing the levels of the neurotransmitters serotonin and norepinephrine, which help regulate mood and may block pain signals traveling through the brain. The researchers noted that use of Cymbalta could result in fewer side effects than the drugs traditionally used for the condition, such as non-steroidal anti-inflammatory drugs, or NSAIDs, which can lead to gastrointestinal bleeding, and opioids like, which often lead to constipation. They concluded that doctors may consider adding antidepressants, such as Cymbalta to the treatment regimens for patients with osteoarthritis. The FDA requires that Cymbalta carry a black-box warning about the risk of suicide among people who use the antidepressant.

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Nancy has a lifetime of experience with depression, experiencing firsthand how devastating this illness can be. Steven Gans, MD is board-certified in psychiatry and is zyprexa zydis 5 mg olanzapine active supervisor, teacher, and mentor at Massachusetts General Hospital. Cymbalta duloxetine hydrochloride is an antidepressant in the serotonin-norepinephrine reuptake inhibitor SNRI category. It is taken by mouth, as a pill or capsule, and can be prescribed for certain depression and anxiety disorders. We also discuss how to take Cymbalta safely, which involves knowing its precautions and contraindications, as well as its potential side effects.

People with depression or mental illness may have cymbalta 60 mg pills about suicide. Some young people may have increased suicidal thoughts when first starting a medicine to treat depression. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide. Duloxetine is used to treat major depressive disorder in adults. Duloxetine is also used to treat general anxiety disorder in adults and children at least 7 years old. Some brands of duloxetine are also used to treat fibromyalgia a chronic pain disorder.

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Cymbalta contains the active drug duloxetine. The active drug is the ingredient that makes a medication work. Drugs that are classified grouped together work in a similar way. Cymbalta comes as delayed-release capsules that you swallow. Delayed-release drugs release slowly into your body over time. Most medications, including Cymbalta, may cause side effects that can be serious or mild.

Common side effects include dry mouth, nausea, feeling tired, dizziness, agitation, sexual problems, and increased sweating. Duloxetine was approved for medical use in the United States in Duloxetine is recommended as a first-line agent for the treatment of chemotherapy-induced neuropathy by the American Society of Clinical Oncology, as a first-line therapy for fibromyalgia in the presence of mood disorders by the German Interdisciplinary Association for Pain Therapy, as a Grade B recommendation for the treatment of diabetic neuropathy by the American Association for Neurology and as a level A recommendation in certain neuropathic states by the European Federation of Neurological Societies. Food and Drug Administration approved duloxetine to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain. In 4 clinical trials of duloxetine for the treatment of MDD, sexual dysfunction occurred significantly more frequently in patients treated with duloxetine than those treated with placebo, and this difference occurred only in men. The suicide attempt rate in the SUI study population based on 9, patients was calculated to be per, person years.