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Leukotriene receptor antagonists are a relatively new class of drugs that directly bind to leukotriene receptors in the lung preventing the inflammatory actions of leukotrienes particularly in the late phase of asthma. They are used in cases of asthma where there is a poor response to bronchodilators alone. Current examples are montelukast and zafirlukast, both of which are given orally, either alone or in combination with corticosteroids.
This is a huge area of therapeutics and there are many drugs available to treat these conditions. Common heart disorders are cardiac failure, ischaemic heart disease and disorders of heart rhythm. Hypertension is included here because many of the drugs used to treat heart disorders are also used in hypertension. A basic knowledge of the physiology of the heart, the mechanism of contraction, electrical activity and control of rate and rhythm, maintenance of blood pressure and what can go wrong is needed in order to understand how the drugs work. The heart consists of four chambers: two atria and two ventricles and is divided into right and left sides.
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The trachea divides into two bronchi, which enter the lungs. The bronchi divide into secondary and tertiary bronchi and further into smaller branches called bronchioles. The airways are lined with ciliated mucosal epithelium. The mucus traps dust and particles and the cilia beat upwards to prevent the mucus and trapped particles from going deeper into the lungs. Bronchioles are supported by smooth muscle, which allows their diameter to change.

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